产品货号:
Z12634
中文名称:
CD169/SIGLEC1抗体
英文名称:
Anti-CD169/SIGLEC1 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD169/SIGLEC1 Antibody |
指标别名 | CD169;Sialoadhesin;SIGLEC 1;SIGLEC1;SN |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,ELISA |
基因名称 | SIGLEC1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human CD169. |
计算分子量 | 183KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | SIGLEC-1,also known as Sialoadhesin or CD169,is a cell adhesion molecule found on the surface of certain cells of the immune system called macrophages.This gene is mapped to 20p13.It belongs to the immunoglobulin superfamily(IgSF).Since sialoadhesin binds sialic acids with its N-terminal IgV-domain,it is also a member of the SIGLEC family.The localization and expression of SIGLEC-1 in humans has altered coincident with the evolutionary loss of Neu5Gc.SIGLEC-1-positive macrophages have a dual physiologic function.They act as innate 'flypaper' by preventing the systemic spread of lymph-borne pathogens and as critical gatekeepers at the lymph-tissue interface that facilitate the recognition of particulate antigens by B cells and initiate humoral immune responses. |
Uniprot ID | Q9BZZ2 |
基因名全称 | Sialoadhesin |
蛋白名全称 | Sialoadhesin |
推荐稀释比 | WB 1:500~1:2000 ELISA 1:20000 |
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